The goal of this article is to show the opportunities and limitations of Robust Design techniques in the design process of developing new applications that combine 3D printing and textiles. Two case studies are discussed in which various elements of Robust Design techniques were used to understand and improve the adhesion strength of 3D printed material on fabric and the pressure exerted by a pneumatic actuator for the purpose of acupressure point manipulation. The advantage of combining 3D printing and textiles is the possibility to transform the properties of a regular textile material by using additive manufacturing. This can be beneficial for the design of specific products and contexts, for example to add mechanical or electronic functions. The experiments presented in this paper were executed as part of an undergraduate course taught to design students in the context of an Industrial Design program.